R-Alpha Lipoic Acid
R-Alpha Lipoic Acid
- potent antioxidant*
- neuroprotective nutrient*
- mitochondrial supportive nutrient*
- anti-inflammatory nutrient*
Stabilized R-Alpha Lipoic Acid (Bio-Enhanced® Na-RALA) is R-(+)-Alpha Lipoic Acid (RALA). It is heat and shelf stable and exhibits high bioavailability. Most alpha-lipoic acid supplements are racemic (i.e., they include equal amounts of the [R] and [S] forms). However, only RALA is the form found naturally in the body. RALA is a unique cofactor in energy production and helps regulate glucose and lipid metabolism.* RALA promotes the synthesis of glutathione and the induction of Phase II detoxification enzymes in the liver.* d-Biotin is a natural cofactor and may complement RALA in promoting mitochondrial health.*
Alpha-lipoic acid (ALA) is a potent antioxidant, anti-inflammatory, neuroprotective, and mitochondrial nutrient. The R-isomer of ALA is a cofactor for mitochondrial enzymes and a substrate for glutathione reductase, it participates in the citric acid cycle and ATP production, and recycles other antioxidants, including vitamins C, E, CoQ10, and glutathione.
R-Alpha-Lipoic Acid provides only the R-isomer, which increased plasma levels nearly 1.5 times higher in older populations than the commonly used racemic mixture (combined R- and S-isomers). ALA has also accelerates wound healing when combined with hyperbaric oxygen therapy, particularly the R-isomer. The R-isomer has a greater neuroprotective effect in an in vivo model of brain vascular injury, due to the S-isomers negative influence or lack of biological activity.
ALA improved glycemic control and insulin resistance in type 2 diabetics, with clear benefit for the prevention and treatment of peripheral neuropathy. It improved endothelial function among individuals with impaired glucose tolerance, and increased weight loss among obese individuals. The R-isomer was significantly more effective than the S-isomer at improving insulin-stimulated glucose transport and metabolism in insulin resistant animal models.
R-Alpha-Lipoic Acid provides only the naturally occurring R-isomer, the only form utilized by mitochondrial enzymes, and only one synthesized in humans
R-isomer has greater biological activity than the racemic mixture often used in supplements, a combination of the R- and S-isomers
R-isomer supplementation results in higher total plasma levels, as well as a shorter time to reach maximum levels in older individuals compared to racemic mixture
ALA neutralizes reactive oxygen species and is a potent inducer of phase 2 antioxidant enzymes
Enhances mitochondrial function and supports glutathione synthesis
Serving Suggestion: Take 1 capsule per day or as directed by your qualified healthcare professional.
Serving Size: One Capsule
Amount Per Serving
d-Biotin … 150 mcg
R-Alpha Lipioc Acid (from 125 mg Sodium R-alpha Lipoate [Bio-Enhanced® Na-Rala]… 100 mg
Other Ingredients: Cellulose, silicon dioxide and magnesium stearate (vegetable source). Capsule consists of gelatin.
No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.
Amount Per Serving d-Biotin 150mcg R-Alpha Lipoic Acid (from 125mg Sodium R-alpha Lipoate [Bio-Enhanced Na-RALA]) 100mg